SCHEMBL8339750

SCHEMBL8339750

CC1(C)CC(N(CCC(=O)NN)C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.38
CTSD P07339 1/20 0.36
POLB P06746 4/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ALOX15 P16050 1/20 0.33
KDM5C P41229 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
MAPT P10636 2/20 0.31
RECQL P46063 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11305541 0.88 GAA (0.38) GAACTSDPOLBKMT2AHTT
SCHEMBL10557784 0.84 GAA (0.37) GAAPOLBKMT2AHTTMEN1
SCHEMBL11295353 0.84 GAA (0.36) GAACTSDPOLBKMT2AHTT
SCHEMBL11404858 0.83 GAA (0.39) GAAPOLBKMT2AHTTKDM4E
SCHEMBL9546369 0.80
SCHEMBL17241788 0.76 ALOX15 (0.44) GAAPOLBKMT2AHTTMEN1
SCHEMBL11396586 0.76 GAA (0.43) GAAKMT2AHTTKDM4EALOX15
SCHEMBL9683857 0.76 GAA (0.55) GAACTSDPOLBKMT2AHTT
SCHEMBL8334264 0.74 GAA (0.61) GAAPOLBKMT2AHTTMEN1
SCHEMBL8338132 0.73 GAA (0.46) GAACTSDPOLBKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238609-B2 Dicarboxylic acid monomers and methods of making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-19 US disclosed
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 US disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 US disclosed
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
US-RE34791-E Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1994-11-15 US disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4975489-A Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending ATOCHEM NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
US-4857595-A Polymer bound hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
US-4824884-A Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-04-25 US disclosed
EP-0310081-A2 A ferroelectric liquid-crystalline polymeric composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-04-05 EP disclosed
EP-0303987-A2 Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME PGD, CDA, PPIA GAA 995/4885CTSD 3217/4885POLB 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.