SCHEMBL11295353

SCHEMBL11295353

CC(=O)N(CCC(=O)NN)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
CTSD P07339 1/20 0.33
HTT P42858 2/20 0.32
POLB P06746 2/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALOX15 P16050 1/20 0.31
KDM5C P41229 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8339750 0.84 GAA (0.38) GAACTSDHTTPOLBKMT2A
SCHEMBL11305541 0.84 GAA (0.38) GAACTSDHTTPOLBKMT2A
SCHEMBL3299682 0.83 ALOX15 (0.37) GAAHTTPOLBKMT2AKDM4E
SCHEMBL17241788 0.81 ALOX15 (0.44) GAAHTTPOLBKMT2AMEN1
SCHEMBL8501436 0.80 ALOX15 (0.35) GAAHTTPOLBKMT2AKDM4E
SCHEMBL7476545 0.79 ALOX15 (0.35) GAAHTTPOLBALOX15
SCHEMBL10587182 0.76 ALOX15 (0.37) GAAHTTPOLBKMT2AMEN1
SCHEMBL13317022 0.76 ALOX15 (0.37) GAAHTTPOLBKMT2AKDM4E
SCHEMBL4417247 0.76 L3MBTL1 (0.35) GAAALOX15
SCHEMBL10557784 0.74 GAA (0.37) GAAHTTPOLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed