Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | TYK2 | P29597 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816712 | 0.89 | KMT2A (0.44) | RAB9AMAPTPOLBALDH1A1KMT2A | |
| SCHEMBL7816214 | 0.85 | RAB9A (0.43) | RAB9AMAPTPOLBALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7829506 | 0.85 | RAB9A (0.44) | RAB9AMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7824577 | 0.84 | MAPT (0.47) | RAB9AMAPTPOLBALDH1A1KMT2A | |
| SCHEMBL7823933 | 0.83 | MAPT (0.48) | RAB9AMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7829184 | 0.81 | SMN1; SMN2 (0.47) | RAB9AMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7827650 | 0.81 | HRH4 (0.41) | MAPTPOLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7829002 | 0.81 | RAB9A (0.48) | MAPK14MAPK11RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7832094 | 0.80 | ALDH1A1 (0.40) | RAB9AMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8345544 | 0.80 | TNF (0.45) | RAB9AMAPTPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |