Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827650 | 0.90 | HRH4 (0.41) | HPGDKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8341651 | 0.85 | RAB9A (0.45) | RAB9AHPGDCNR1CNR2KMT2A | |
| SCHEMBL7816712 | 0.82 | KMT2A (0.44) | RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL8339795 | 0.81 | MAPK14 (0.43) | RAB9AKMT2AMAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL7824577 | 0.78 | MAPT (0.47) | RAB9AHPGDKMT2ATSHRNPC1 | |
| SCHEMBL7823933 | 0.76 | MAPT (0.48) | RAB9AKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7827224 | 0.76 | KDM4E (0.49) | RAB9ACNR1CNR2KMT2ATSHR | |
| SCHEMBL8800003 | 0.76 | ALDH1A1 (0.41) | CNR1CNR2KMT2ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL7829506 | 0.76 | RAB9A (0.44) | RAB9AKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7829184 | 0.75 | SMN1; SMN2 (0.47) | RAB9AHPGDKMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |