SCHEMBL8340236

SCHEMBL8340236

CCCCCCCCCCCCCCCCCCc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.51
LPL P06858 5/20 0.47
LIPG Q9Y5X9 5/20 0.47
KAT8 Q9H7Z6 2/20 0.45
PPARA Q07869 1/20 0.45
MGLL Q99685 2/20 0.45
TRPV1 Q8NER1 1/20 0.45
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28136660 1.00 GPR3 (0.51) GPR3LPLLIPGKAT8PPARA
SCHEMBL8344457 1.00 GPR3 (0.51) GPR3LPLLIPGKAT8PPARA
SCHEMBL2675582 1.00 GPR3 (0.51) GPR3LPLLIPGKAT8PPARA
SCHEMBL6407122 1.00 GPR3 (0.51) GPR3LPLLIPGKAT8PPARA
SCHEMBL6407464 1.00 GPR3 (0.51) GPR3LPLLIPGKAT8PPARA
SCHEMBL2363419 0.98 GPR3 (0.49) GPR3LPLLIPGKAT8PPARA
SCHEMBL6412562 0.93 SKP2 (0.43) GPR3LPLLIPGALDH1A1LMNA
SCHEMBL17250898 0.91 ALOX15 (0.44) GPR3LPLLIPGALDH1A1LMNA
SCHEMBL10001961 0.91 ALOX15 (0.44) GPR3LPLLIPGALDH1A1LMNA
SCHEMBL20251159 0.91 ALOX15 (0.44) GPR3LPLLIPGALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1092095-C Abrasive article comprising antiloading component MINNESOTA MINING & MFG (US) 2002-10-09 CN claimed
CN-1217679-A Abrasive article comprising antiloading component MINNESOTA MINING & MFG (US) 1999-05-26 CN claimed
EP-0912295-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-05-06 EP claimed
US-5704952-A COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-06 US claimed
WO-1997042007-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-13 WO claimed
US-5954844-A BACKING SUPPORTING SURFACE-BOUND ABRASIVE PARTICLES AND ANTILOADING COMPOUND COMPRISING AN ALKYLATED OR FLUOROALKYLATED ORGANOBORON, ORGANONITROGEN, ORGANOPHOSPHORUS, ORGANOSULFUR, OR HYDROXYCARBOXYLIC ACID DERIVATIVE MINNESOTA MINING & MANUFACTURING COMPANY (US) 1999-09-21 US disclosed
EP-0912295-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-05-06 EP disclosed
US-5704952-A COATINGS, BONDING, NONWOVEN ABRASIVES AND BINDERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-06 US disclosed
WO-1997042007-A1 ABRASIVE ARTICLE COMPRISING AN ANTILOADING COMPONENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-13 WO disclosed