Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 8/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457597 | 0.88 | HDAC4 (0.56) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6455095 | 0.87 | MMP12 (0.71) | MMP12MMP13MMP3MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL6881474 | 0.86 | MMP12 (0.70) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6882247 | 0.84 | MMP12 (0.56) | MMP12MMP13MMP3MMP9MMP8 | |
| SCHEMBL6450858 | 0.77 | HDAC6 (0.57) | MMP12MMP13ROCK2HDAC4HDAC6 | |
| SCHEMBL6456462 | 0.77 | MMP12 (0.72) | MMP12HDAC4HDAC6HIF1A | |
| SCHEMBL6874296 | 0.76 | MMP12 (0.68) | MMP12HDAC4HDAC6MAPK14 | |
| SCHEMBL6452267 | 0.76 | MMP12 (0.68) | MMP12HDAC4HDAC6MAPK14 | |
| SCHEMBL6463535 | 0.76 | MMP12 (0.88) | MMP12MMP13MMP8HDAC4HDAC6 | |
| SCHEMBL6882179 | 0.74 | MMP12 (0.57) | MMP12MMP13MMP8HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018448-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |