Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346225 | 1.00 | PRSS1 (0.52) | PRSS1F2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8345500 | 0.85 | PRSS1 (0.45) | PRSS1F2PRMT5TMEM97SIGMAR1 | |
| SCHEMBL8342340 | 0.85 | PRSS1 (0.45) | PRSS1F2PRMT5TMEM97SIGMAR1 | |
| SCHEMBL14992654 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHTTSTS | |
| SCHEMBL3636928 | 0.84 | PARP1 (0.46) | KLK7PRMT5PARP1TMEM97SIGMAR1 | |
| SCHEMBL2961611 | 0.83 | TMEM97 (0.50) | SMN1; SMN2NPC1RAB9AHTTSTS | |
| Hydrochloric Acid SCHEMBL8342347 | 0.82 | PRSS1 (0.49) | PRSS1F2KLK7TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8345629 | 0.82 | PRSS1 (0.49) | PRSS1F2KLK7TMEM97SIGMAR1 | |
| SCHEMBL27140910 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AHTTSTS | |
| Hydrochloric Acid SCHEMBL8342349 | 0.82 | PRSS1 (0.49) | PRSS1F2KLK7TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |