Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342340 | 1.00 | PRSS1 (0.45) | PRSS1F2FKBP1APDE4BPRMT5 | |
| SCHEMBL8340452 | 0.85 | PRSS1 (0.52) | PRSS1F2FKBP1APRMT5TMEM97 | |
| SCHEMBL8346225 | 0.85 | PRSS1 (0.52) | PRSS1F2FKBP1APRMT5TMEM97 | |
| SCHEMBL16755116 | 0.79 | MEN1 (0.46) | PDE4BTMEM97SIGMAR1CTSLNPSR1 | |
| SCHEMBL16755117 | 0.79 | MEN1 (0.46) | PDE4BTMEM97SIGMAR1CTSLNPSR1 | |
| SCHEMBL8344277 | 0.78 | PRSS1 (0.44) | PRSS1F2 | |
| SCHEMBL8345142 | 0.78 | PRSS1 (0.44) | PRSS1F2 | |
| SCHEMBL19410248 | 0.77 | ALDH1A1 (0.48) | CTSLNPSR1MEN1KMT2A | |
| SCHEMBL8345660 | 0.76 | PRSS1 (0.43) | PRSS1F2MEN1KMT2A | |
| SCHEMBL8345820 | 0.76 | PRSS1 (0.54) | PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |