Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342286 | 0.88 | UTS2R (0.43) | NPSR1MEN1MAPTKMT2APTGS1 | |
| SCHEMBL8342515 | 0.87 | TSHR (0.51) | HDAC2NPSR1MEN1KMT2AHSD17B10 | |
| SCHEMBL8346045 | 0.76 | SLC1A3 (0.46) | NPSR1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL8347059 | 0.72 | MEN1 (0.47) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL12262967 | 0.72 | SLC1A2 (0.63) | HDAC2MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL10373167 | 0.69 | HSD17B10 (0.68) | HDAC2MEN1MAPTKMT2APTGS1 | |
| SCHEMBL3486347 | 0.67 | MAPT (0.61) | HDAC2MAPTPTGS1P2RX1KDM4E | |
| SCHEMBL8345976 | 0.67 | ALDH1A1 (0.44) | NPSR1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL13890815 | 0.67 | GPR139 (0.65) | NPSR1MEN1KMT2AALDH1A1KCNK3 | |
| SCHEMBL7058699 | 0.67 | PTGS1 (0.45) | MEN1MAPTKMT2APTGS1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |