Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346828 | 0.79 | GAA (0.47) | ALDH1A1KDM4EHPGDPKMMAPT | |
| SCHEMBL10103694 | 0.73 | PDE2A (0.49) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL8346045 | 0.72 | SLC1A3 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL19019674 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL14100033 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL8116399 | 0.68 | CFTR (0.44) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL20093090 | 0.67 | ALOX5AP (0.49) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL8340565 | 0.67 | HDAC2 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL26906947 | 0.67 | KIF11 (0.57) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL28090529 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |