Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21260801 | 0.85 | ESR1 (0.78) | ESR1MAOBESR2 | |
| SCHEMBL8341280 | 0.83 | ESR1 (0.86) | ESR1KMT2AMAOBESR2 | |
| SCHEMBL8340581 | 0.82 | ESR1 (0.74) | ESR1MAOBESR2 | |
| SCHEMBL8341825 | 0.78 | ESR1 (0.50) | ESR1KMT2AMAOBALDH1A1MAPT | |
| SCHEMBL8341396 | 0.78 | ESR1 (0.76) | ESR1KMT2AESR2MAPT | |
| SCHEMBL11599719 | 0.77 | ESR1 (0.47) | ESR1KMT2AMAOBALDH1A1GAA | |
| SCHEMBL8340562 | 0.77 | MAOB (0.55) | ESR1KMT2AMAOBALDH1A1MAPT | |
| SCHEMBL11599689 | 0.77 | ESR1 (0.71) | ESR1KMT2AESR2GAAMAPT | |
| SCHEMBL15660907 | 0.76 | ESR1 (1.00) | ESR1MAOBESR2 | |
| SCHEMBL8341726 | 0.76 | ESR1 (0.74) | ESR1KMT2AMAOBESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908859-A | ESPECIALLY HYPERCHOLESTEROLEMIA | ELI LILLY AND COMPANY (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0897918-A1 | Benzothiophene derivatives and their use as pharmaceutically active agents | ELI LILLY AND COMPANY (US) | 1999-02-24 | — | — | EP | disclosed |