Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 9/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560853 | 0.76 | PARP1 (0.41) | PNPADORA3ACHEGDAALDH1A1 | |
| SCHEMBL3845982 | 0.66 | — | — | |
| SCHEMBL3941170 | 0.65 | ACHE (0.40) | JAK2PNPADORA3ACHEGDA | |
| SCHEMBL1992700 | 0.65 | PARP1 (0.41) | ACHEGDAALDH1A1LMNA | |
| SCHEMBL10518128 | 0.65 | ALDH1A1 (0.53) | PNPADORA3ACHEGDAALDH1A1 | |
| SCHEMBL1993929 | 0.64 | ADORA2A (0.40) | PNPADORA3ACHEGDAALDH1A1 | |
| SCHEMBL8667323 | 0.64 | PNP (0.53) | PNPALDH1A1 | |
| SCHEMBL5438527 | 0.63 | ACHE (0.36) | ADORA3ACHEGDAALDH1A1LMNA | |
| SCHEMBL19181967 | 0.63 | PNP (0.37) | PNP | |
| SCHEMBL8340805 | 0.62 | PNP (0.36) | JAK2JAK1PNPGDAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874578-A | Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process | BRISTOL-MYERS SQUIBB (US) | 1999-02-23 | — | — | US | disclosed |