SCHEMBL8340894

SCHEMBL8340894

CC(C)(OOC(C)(C)C(c1ccccc1)(c1ccccc1)c1ccccc1)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 1/20 0.46
TAAR1 Q96RJ0 1/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP3A4 P08684 1/20 0.39
KCNN4 O15554 4/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.38
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP2B6 P20813 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4358877 0.86 MAPK1 (0.48) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL704059 0.80 MAPK1 (0.46) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL10892418 0.80 MAPK1 (0.42) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL4462028 0.78 MAPK1 (0.44) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL4462032 0.75 ALDH1A1 (0.43) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL6552913 0.75 ALDH1A1 (0.43) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL8216938 0.75 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL9356439 0.73 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL8178 0.73 KCNN4 (0.53) MAPK1ALDH1A1ALOX15TAAR1ESR1
Benzene SCHEMBL25312146 0.72 MAPK1 (1.00) MAPK1ALDH1A1ALOX15TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985513-A POLYSILANES AND BENZOPHENONES KABUSHIKI KAISHA TOSHIBA (JP) 1999-11-16 US disclosed
US-5962581-A POLYSILANE; IRRADIATING WITH ACTINIC RADIATION; REMOVAL SEGMENTS BY DISSOLVING IN AQUEOUS ALKALINE DEVELOPER KABUSHIKI KAISHA TOSHIBA (JP) 1999-10-05 US disclosed
US-4831063-A RAPID CURING OF AN UNSATURATED EPOXY/ORGANOALUMINUM COMPOUND MIXTURE BY ADDING A SILYLPEROXY COMPOUND; PAINTS; COATINGS KABUSHIKI KAISHA TOSHIBA (JP) 1989-05-16 US disclosed
EP-0135887-A2 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-04-03 EP disclosed