Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PMM2 | O15305 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345599 | 0.84 | ALDH1A1 (0.32) | ALDH1A1CYP1A2LMNAKDM4EKMT2A | |
| SCHEMBL8345319 | 0.83 | ALDH1A1 (0.39) | ALDH1A1USP2HSD17B10LMNAMAPT | |
| SCHEMBL8342309 | 0.82 | KDM4E (0.32) | ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL7141262 | 0.80 | KDM4E (0.31) | ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL8340912 | 0.80 | MAPT (0.33) | NPC1ALDH1A1HSD17B10LMNAMAPT | |
| SCHEMBL9221707 | 0.79 | ATM (0.52) | ATMNPC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7135299 | 0.78 | — | — | |
| SCHEMBL6983998 | 0.78 | — | — | |
| SCHEMBL8340623 | 0.77 | — | — | |
| SCHEMBL7469151 | 0.76 | ALPL (0.37) | PMM2MIFMPIPHOSPHO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014216-A1 | SUBSTITUTED 3(-1,2-BENZISOTHIAZOL OR ISOXAZOL-5 YL)-SUBSTITUTED PYRIMIDINE AS HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |