Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816995 | 0.87 | MEN1 (0.41) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7815783 | 0.86 | MEN1 (0.44) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL8799254 | 0.85 | KMT2A (0.40) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7827815 | 0.83 | MEN1 (0.44) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL8345228 | 0.83 | PTGES (0.43) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7823417 | 0.82 | MEN1 (0.43) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7831438 | 0.81 | AKR1B1 (0.42) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7823605 | 0.81 | KMT2A (0.41) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7824810 | 0.80 | SMN1; SMN2 (0.41) | MEN1KMT2ACRHBPHTTCRHR2 | |
| SCHEMBL7831629 | 0.80 | GHSR (0.42) | MEN1KMT2ACRHBPHTTCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |