Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823605 | 0.89 | KMT2A (0.41) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7815783 | 0.87 | MEN1 (0.44) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7827815 | 0.87 | MEN1 (0.44) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7832320 | 0.87 | MAPT (0.42) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7823417 | 0.86 | MEN1 (0.43) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL7816944 | 0.86 | KMT2A (0.42) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7816337 | 0.85 | KDM4E (0.41) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL8342243 | 0.85 | GHSR (0.39) | MEN1KMT2APOLBRAB9ACRHBP | |
| SCHEMBL7827960 | 0.85 | ALDH1A1 (0.40) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL7831438 | 0.85 | AKR1B1 (0.42) | MEN1KMT2APOLBRAB9ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |