1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL8342218

C=C(C)C(=O)OC.C=C(C=CC(=O)O)C(=O)OCC.C=C(Cl)Cl.C=CC#N

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
TSHR P16473 2/20 0.37
HCAR2 Q8TDS4 1/20 0.36
CYP2C9 P11712 1/20 0.31
THRB P10828 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL5586489 0.90 ALDH1A1 (0.43) ALDH1A1TSHRHCAR2
Acrylonitrile SCHEMBL9282459 0.87 ALDH1A1 (0.47) ALDH1A1TSHRHCAR2CYP2C9THRB
SCHEMBL770780 0.87 ALDH1A1 (0.48) ALDH1A1TSHRHCAR2THRB
1,1-Dichloroethene SCHEMBL9581851 0.85 ALDH1A1 (0.35) ALDH1A1TSHRHCAR2
Methacrylic Acid SCHEMBL8982580 0.84 ALDH1A1 (0.46) ALDH1A1TSHRHCAR2THRB
Acrolein SCHEMBL11766257 0.83 ALDH1A1 (0.42) ALDH1A1TSHRHCAR2THRB
Acrylic Acid SCHEMBL11314595 0.83 ALDH1A1 (0.44) ALDH1A1TSHRHCAR2CYP2C9THRB
Acrylic Acid Ethyl Ester SCHEMBL8342221 0.82 ALDH1A1 (0.39) ALDH1A1TSHRHCAR2THRB
1,1-Dichloroethene SCHEMBL6373416 0.81 HCAR2 (0.52) ALDH1A1TSHRHCAR2
Acrylic Acid Ethyl Ester SCHEMBL4626297 0.80 HCAR2 (0.44) ALDH1A1TSHRHCAR2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5928835-A WITH LAYER CONTAINING HYDRAZINE DERIVATIVE KONICA CORPORATION (JP) 1999-07-27 US disclosed
EP-0754966-A1 Silver halide light-sensitive photographic material and processing method thereof KONICA CORPORATION (JP) 1997-01-22 EP disclosed