Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 9/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | ULK1 | O75385 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878778 | 0.87 | MMP12 (0.69) | MMP12MMP13ALDH1A1HPGDABL1 | |
| SCHEMBL6882182 | 0.85 | MMP12 (0.57) | MMP12MMP13ABL1EPHX2PPARG | |
| SCHEMBL8301905 | 0.83 | MMP12 (0.78) | MMP12MMP13ABL1EPHX2PPARG | |
| SCHEMBL6451093 | 0.82 | MMP12 (0.64) | MMP12MMP13ABL1EPHX2PPARG | |
| SCHEMBL6883411 | 0.80 | MMP12 (0.64) | MMP12MMP13ABL1SCN10AMMP3 | |
| SCHEMBL8300026 | 0.79 | MMP12 (0.66) | MMP12MMP13ABL1POLBMAPT | |
| SCHEMBL8300028 | 0.78 | MMP12 (0.58) | MMP12MMP13ABL1EPHX2PPARG | |
| SCHEMBL6451092 | 0.78 | MMP12 (0.59) | MMP12MMP13ABL1SCN10AULK1 | |
| SCHEMBL6468492 | 0.78 | MMP12 (0.63) | MMP12MMP13ABL1EPHX2SCN10A | |
| SCHEMBL8339575 | 0.77 | MMP12 (0.58) | MMP12MMP13ALDH1A1HPGDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018448-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |