Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340981 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL29274259 | 0.75 | ALDH1A1 (0.66) | ALDH1A1TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL301933 | 0.75 | ALDH1A1 (0.69) | ALDH1A1HTTTSHRTDP1L3MBTL1 | |
| SCHEMBL9376368 | 0.74 | TXNRD1 (0.40) | ALDH1A1TSHRTDP1L3MBTL1KDM4E | |
| SCHEMBL10508062 | 0.73 | AR (0.52) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL6178841 | 0.73 | MAPK1 (0.51) | ALDH1A1HTTTDP1L3MBTL1GAA | |
| Ammonia Solution, Strong SCHEMBL10338964 | 0.73 | ALDH1A1 (0.67) | ALDH1A1HTTTSHRTDP1L3MBTL1 | |
| SCHEMBL10507124 | 0.73 | AR (0.51) | ALDH1A1HTTTSHRL3MBTL1KDM4E | |
| SCHEMBL261866 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HTTTSHRTDP1L3MBTL1 | |
| SCHEMBL10505643 | 0.70 | AR (0.49) | ALDH1A1TSHRKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885935-A | Sulfonamide herbicides | AGREVO UK LIMITED (GB) | 1999-03-23 | — | — | US | disclosed |
| EP-0625970-B1 | SULFONAMIDE HERBICIDES | AGREVO UK LTD (GB) | 1997-09-17 | — | — | EP | disclosed |
| US-5559081-A | Sulfonamide herbicides | AGREVO UK LIMITED (GB) | 1996-09-24 | — | — | US | disclosed |