Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524802 | 0.81 | MEN1 (0.46) | MEN1KMT2AGPR55ALDH1A1GAA | |
| SCHEMBL21752944 | 0.81 | CASP1 (0.49) | MMP2ACECASP1MEN1KMT2A | |
| SCHEMBL30494477 | 0.79 | MME (0.56) | ACE | |
| SCHEMBL11061682 | 0.79 | ACE (0.56) | ACEPREP | |
| SCHEMBL7864413 | 0.79 | ACE (0.56) | ACEPREP | |
| SCHEMBL7864412 | 0.79 | ACE (0.56) | ACEPREP | |
| SCHEMBL8342335 | 0.79 | XIAP (0.49) | CASP1PREPALDH1A1GAA | |
| SCHEMBL28777589 | 0.79 | CASP1 (0.48) | ACECASP1PREPALDH1A1GAA | |
| SCHEMBL8339321 | 0.78 | ALDH1A1 (0.46) | CASP1MEN1KMT2APREPGPR55 | |
| SCHEMBL21752950 | 0.78 | CASP1 (0.48) | CASP1MEN1KMT2APREPGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |