Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343951 | 0.94 | MTNR1B (0.43) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL8346145 | 0.87 | HTR1A (0.43) | HTR1AHTR1DHTR1BSIGMAR1HTR2A | |
| SCHEMBL8344543 | 0.81 | MTNR1B (0.43) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL8344546 | 0.81 | SIGMAR1 (0.53) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL8346070 | 0.75 | MTNR1B (0.41) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL27529224 | 0.75 | MTNR1B (0.61) | MTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL8347285 | 0.75 | MTNR1B (0.61) | MTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL8343949 | 0.75 | MTNR1B (0.44) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL8343954 | 0.74 | SIGMAR1 (0.58) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL8349189 | 0.73 | MTNR1B (0.46) | MTNR1BHTR1AHTR1DHTR1BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929078-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | claimed |
| US-5929078-A | ANTISEROTONINE AGENT | SYNTHELABO (FR) | 1999-07-27 | — | — | US | disclosed |