Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 15/20 | 0.58 |
| ▸ | SLC2A3 | P11169 | 15/20 | 0.58 |
| ▸ | SLC2A2 | P11168 | 9/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL838951 | 0.81 | SLC2A1 (0.65) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL838296 | 0.80 | SLC2A1 (0.66) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL6205196 | 0.79 | SLC2A1 (0.65) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL6224888 | 0.78 | GSK3B (0.62) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| Hydrochloric Acid SCHEMBL6205326 | 0.77 | GSK3B (0.61) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL15105528 | 0.71 | CYP17A1 (0.62) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL8344245 | 0.70 | TP53 (0.49) | GSK3BMAPTLMNATP53CYP1A2 | |
| SCHEMBL25343478 | 0.69 | MAPT (0.52) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL15105468 | 0.68 | CYP17A1 (0.70) | SLC2A1SLC2A3SLC2A2GSK3BCYP17A1 | |
| SCHEMBL15105690 | 0.68 | CYP17A1 (0.57) | SLC2A1SLC2A3SLC2A2GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |