Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.56 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.56 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839657 | 0.85 | SLC2A1 (0.54) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL8344398 | 0.81 | LMNA (0.67) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL24393325 | 0.81 | ALDH1A1 (0.67) | LMNAHTTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15113006 | 0.76 | GSK3B (0.49) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL15113007 | 0.74 | SLC2A1 (0.46) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL30948485 | 0.74 | HTT (0.72) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL3424926 | 0.74 | TP53 (0.54) | SLC2A1SLC2A2SLC2A3GSK3BLMNA | |
| SCHEMBL368464 | 0.71 | CYP17A1 (0.77) | GSK3B | |
| SCHEMBL3612259 | 0.71 | FSCN1 (0.54) | LMNAHTTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL13082426 | 0.71 | NPC1 (0.56) | LMNAHTTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |