Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556904 | 0.82 | MAOA (0.49) | MAOBALDH1A1MAOAMTNR1AMTNR1B | |
| SCHEMBL29427899 | 0.82 | MAOA (0.49) | MAOBKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL983738 | 0.82 | MAOA (0.49) | MAOBKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL950483 | 0.81 | KDM1A (0.43) | MAOBHSD17B3MAOAKDM1ASMN1; SMN2 | |
| SCHEMBL7911204 | 0.80 | CA12 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2GPR84 | |
| SCHEMBL31090834 | 0.80 | CA12 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2GPR84 | |
| SCHEMBL18599627 | 0.80 | GAA (0.43) | MAOBKDM4EALDH1A1MAOAKDM1A | |
| Trimethylammonium SCHEMBL10874742 | 0.80 | MAOA (0.44) | MAOBKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL10647437 | 0.79 | GPR84 (0.43) | MAOBKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL15821065 | 0.78 | HDAC6 (0.44) | MAOBKDM4EMAOAKDM1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58039638-A | — | — | None | — | — | JP | disclosed |
| WO-2004085408-A1 | 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2004-10-07 | — | — | WO | disclosed |
| EP-0177222-B1 | CYCLOHEXANE-1,3-DIONE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PROCESSES FOR PREPARING THEM, AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1990-06-27 | — | — | EP | disclosed |
| US-4604128-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-08-05 | — | — | US | disclosed |
| EP-0177222-A1 | Cyclohexane-1,3-dione derivatives, compositions containing them, processes for preparing them, and their use as herbicides and plant growth regulators | ICI AUSTRALIA LIMITED (AU) | 1986-04-09 | — | — | EP | disclosed |
| JP-S5839638-A | NOVEL PREPARATION OF 2-ACETYL-3,4-DIHYDRONAPHTHALENES | SUMITOMO CHEM CO LTD | 1983-03-08 | — | — | JP | disclosed |