Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 14/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 14/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 14/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 14/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 7/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.55 |
| ▸ | GRIK4 | Q16099 | 7/20 | 0.55 |
| ▸ | GRIK5 | Q16478 | 7/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704936 | 0.73 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL31653996 | 0.73 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610724 | 0.72 | FDPS (0.48) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7359701 | 0.71 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610110 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8609960 | 0.69 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL14199352 | 0.69 | KDM4E (0.38) | GRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL18180193 | 0.68 | APEX1 (0.77) | APEX1MEN1KMT2A | |
| SCHEMBL8191230 | 0.66 | GRIA1 (0.62) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL4591850 | 0.65 | MAPT (0.63) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |