SCHEMBL8345006

SCHEMBL8345006

CCC(N)(CC)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.43
CHRM1 P11229 1/20 0.43
TBXA2R P21731 1/20 0.43
ADRA1A P35348 1/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.42
CYP2C19 P33261 2/20 0.42
HIF1A Q16665 2/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
FFAR3 O14843 2/20 0.40
FFAR1 O14842 1/20 0.37
CPT2 P23786 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9538481 0.94 HMGCR (0.43) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL5320897 0.87 KDM4E (0.48) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL16374685 0.82 ALDH1A1 (0.45) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL9539930 0.80 MEN1 (0.34) HMGCRCHRM1TBXA2RADRA1AALDH1A1
Bicarbonate SCHEMBL4357750 0.79 MEN1 (0.42) ALDH1A1MEN1CYP1A2THRBKMT2A
Hydrochloric Acid SCHEMBL27533813 0.79 KDM4E (0.48) HMGCRCHRM1TBXA2RADRA1AALDH1A1
Citric Acid SCHEMBL6727157 0.79 ALDH1A1 (0.65) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL16838734 0.78 ALDH1A1 (0.40) ALDH1A1MEN1CYP1A2THRBKMT2A
SCHEMBL5664856 0.78
SCHEMBL6234394 0.78 CYP1A2 (0.33) ALDH1A1MEN1CYP1A2THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999015694-A1 COREACTANT-INCLUDING ELECTROCHEMILUMINESCENT COMPOUNDS, METHODS, SYSTEMS AND KITS UTILIZING SAME IGEN INTERNATIONAL, INC. (US) 1999-04-01 WO disclosed
US-4217238-A BASIC SALT, SCRUBBING EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-12 US disclosed
US-4094957-A CARBON DIOXIDE EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed