Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344155 | 1.00 | CTSS (0.51) | CTSSCTSKCA2LMNAPOLB | |
| SCHEMBL8347951 | 1.00 | CTSS (0.51) | CTSSCTSKCA2LMNAPOLB | |
| SCHEMBL9567473 | 0.87 | CTSS (0.49) | CTSSCTSKCA2GLSMEN1 | |
| SCHEMBL8347748 | 0.86 | PGR (0.53) | LMNAPOLBPGRSCN1ASCN2A | |
| SCHEMBL9670280 | 0.86 | AAK1 (0.52) | CTSSCTSKCA2LMNAPOLB | |
| SCHEMBL8345568 | 0.85 | NPC1 (0.45) | CTSSCTSKLMNAPOLBPGR | |
| SCHEMBL21731607 | 0.82 | CTSS (0.58) | CTSSCTSKCA2LMNAGLS | |
| SCHEMBL21731703 | 0.82 | CTSS (0.58) | CTSSCTSKCA2LMNAGLS | |
| SCHEMBL3235114 | 0.81 | CTSS (0.51) | CTSSCTSKGLSMEN1KMT2A | |
| SCHEMBL3495258 | 0.81 | CTSS (0.51) | CTSSCTSKGLSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |