Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008297 | 0.81 | FFAR1 (0.57) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8343697 | 0.81 | FFAR1 (0.57) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8014867 | 0.79 | FFAR1 (0.50) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8008244 | 0.78 | FFAR1 (0.49) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8345213 | 0.74 | LMNA (0.50) | LTA4HBCHEFFAR1FFAR4LMNA | |
| SCHEMBL8880568 | 0.73 | LTA4H (0.64) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8085894 | 0.72 | MAOB (0.64) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL11623563 | 0.72 | MAOB (0.55) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL8887471 | 0.71 | LTA4H (0.60) | MAOBLTA4HEPHX2BCHEFFAR1 | |
| SCHEMBL28064099 | 0.70 | FFAR1 (0.58) | MAOBLTA4HEPHX2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014210-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRAN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-03-25 | — | — | WO | claimed |
| WO-1999014210-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 5,6-DIHYDRO-2H-PYRAN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |