Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346970 | 0.83 | CTSS (0.60) | S1PR3CTSSCTSKTSHRHSD17B10 | |
| SCHEMBL14551912 | 0.80 | S1PR3 (0.47) | S1PR3CTSSCTSK | |
| SCHEMBL8328193 | 0.76 | CTSS (0.55) | S1PR3CTSSCTSKLCKMEN1 | |
| SCHEMBL8337687 | 0.76 | CTSS (0.57) | HTTSMN1; SMN2S1PR3CTSSCTSK | |
| SCHEMBL8337684 | 0.76 | CTSS (0.54) | S1PR3CTSSCTSKMEN1THRB | |
| SCHEMBL2839359 | 0.75 | S1PR3 (0.44) | LMNAHTTSMN1; SMN2NPSR1S1PR3 | |
| SCHEMBL30371015 | 0.75 | S1PR3 (0.46) | S1PR3CTSSCTSK | |
| SCHEMBL20588318 | 0.75 | S1PR3 (0.46) | S1PR3CTSSCTSK | |
| SCHEMBL6713811 | 0.74 | LMNA (0.54) | LMNAHTTSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL6716913 | 0.74 | ALDH1A1 (0.47) | LMNAHTTSMN1; SMN2NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |