Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804997 | 0.88 | GPR35 (0.39) | KDM4EALDH1A1NPSR1TSHRHSD17B10 | |
| SCHEMBL7823605 | 0.88 | KMT2A (0.41) | ALDH1A1GHSRMAPTMEN1KMT2A | |
| SCHEMBL7832320 | 0.86 | MAPT (0.42) | ALDH1A1NPSR1TDP1GHSRGPR35 | |
| SCHEMBL8345228 | 0.85 | PTGES (0.43) | GHSRMAPTMEN1KMT2APOLB | |
| SCHEMBL7827960 | 0.84 | ALDH1A1 (0.40) | ALDH1A1GHSRMAPTMEN1KMT2A | |
| SCHEMBL7827815 | 0.84 | MEN1 (0.44) | ALDH1A1NPSR1GHSRGPR35MAPT | |
| SCHEMBL7816960 | 0.83 | KDM4E (0.38) | KDM4ETDP1L3MBTL1GHSRGPR35 | |
| SCHEMBL7831438 | 0.82 | AKR1B1 (0.42) | HSD17B10GHSRGPR35MAPTMEN1 | |
| SCHEMBL7815783 | 0.82 | MEN1 (0.44) | ALDH1A1NPSR1GHSRGPR35MAPT | |
| SCHEMBL7828350 | 0.82 | TP53 (0.41) | KDM4EALDH1A1TSHRTDP1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |