Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ACP3 | P15309 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237816 | 0.83 | HDAC6 (0.36) | RIPK1CYP2C19HIF1AGAACYP1A2 | |
| SCHEMBL8060409 | 0.78 | KCNN4 (0.43) | RIPK1CES2CES1RAB9AACP3 | |
| SCHEMBL187685 | 0.76 | CYP2C19 (0.46) | CYP2C19HIF1ACYP1A2MAPTKMT2A | |
| SCHEMBL9229179 | 0.73 | ACP3 (0.47) | ACP3 | |
| SCHEMBL25845086 | 0.68 | RIPK1 (0.36) | RIPK1CES2CES1GAATRPA1 | |
| SCHEMBL8342905 | 0.68 | RIPK1 (0.33) | RIPK1CES2CES1GAATRPA1 | |
| SCHEMBL4937243 | 0.67 | ENO1 (0.42) | LMNAKMT2A | |
| SCHEMBL31294785 | 0.66 | CYP2C19 (0.50) | RIPK1CES2CES1CYP2C19HIF1A | |
| SCHEMBL25256176 | 0.66 | RIPK1 (0.31) | RIPK1TRPA1 | |
| SCHEMBL19618115 | 0.66 | RIPK1 (0.40) | RIPK1CES2CES1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012899-A1 | A PROCESS FOR MAKING PROSTAGLANDIN F ANALOGS | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-18 | — | — | WO | disclosed |