Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345080 | 0.86 | MEN1 (0.52) | FAAHTRPV1KMT2A | |
| SCHEMBL8344329 | 0.84 | KMT2A (0.50) | FAAHTRPV1KMT2A | |
| SCHEMBL8345466 | 0.84 | FAAH (0.47) | ALDH1A1FAAHTRPV1KMT2A | |
| SCHEMBL8345090 | 0.83 | FAAH (0.49) | ALDH1A1FAAHTRPV1SMN1; SMN2KMT2A | |
| SCHEMBL8347812 | 0.83 | FAAH (0.47) | ALDH1A1FAAHTRPV1KMT2A | |
| SCHEMBL8346749 | 0.80 | GHSR (0.47) | ALDH1A1FAAHTRPV1PDK1PDK2 | |
| SCHEMBL29991357 | 0.78 | KMT2A (0.59) | L3MBTL1ALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL729221 | 0.78 | KMT2A (0.59) | L3MBTL1ALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL25384603 | 0.78 | FAAH (0.62) | ALDH1A1FAAHTRPV1 | |
| SCHEMBL31075550 | 0.77 | FAAH (0.65) | ALDH1A1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |