Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403058 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL3829139 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL6311490 | 0.88 | KEAP1 (0.67) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL6314266 | 0.84 | KMT2A (0.56) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL6314587 | 0.84 | KMT2A (0.56) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL19309522 | 0.83 | LMNA (0.58) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL6314202 | 0.82 | TP53 (0.56) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL5680826 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL6405411 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 | |
| SCHEMBL15779510 | 0.82 | LMNA (0.56) | ALDH1A1KMT2ANPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |