Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.45 |
| ▸ | RARG | P13631 | 7/20 | 0.45 |
| ▸ | RARA | P10276 | 5/20 | 0.45 |
| ▸ | RXRA | P19793 | 11/20 | 0.44 |
| ▸ | RXRG | P48443 | 8/20 | 0.44 |
| ▸ | RXRB | P28702 | 8/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555708 | 0.90 | RXRA (0.52) | RARBRARGRARARXRARXRG | |
| SCHEMBL8556718 | 0.89 | RXRA (0.55) | RARBRARGRARARXRARXRG | |
| SCHEMBL8555445 | 0.87 | RXRA (0.52) | RARBRXRARXRGRXRBHNF4A | |
| SCHEMBL8557640 | 0.87 | RXRA (0.52) | RARBRXRARXRGRXRBHNF4A | |
| SCHEMBL8555502 | 0.87 | RXRA (0.52) | RARBRXRARXRGRXRBHNF4A | |
| SCHEMBL8556422 | 0.87 | RXRA (0.52) | RARBRXRARXRGRXRBHNF4A | |
| SCHEMBL7876784 | 0.87 | RARB (0.57) | RARBRARGRARARXRARXRG | |
| SCHEMBL7876787 | 0.87 | RARB (0.57) | RARBRARGRARARXRARXRG | |
| SCHEMBL8346574 | 0.86 | RXRA (0.41) | RARBRARGRARARXRARXRG | |
| SCHEMBL8559124 | 0.86 | HNF4A (0.48) | RARBRARGRARARXRARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | claimed |
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | disclosed |