Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.41 |
| ▸ | RXRB | P28702 | 9/20 | 0.41 |
| ▸ | RXRG | P48443 | 9/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARG | P13631 | 3/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883321 | 0.80 | RXRA (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8347055 | 0.79 | RXRA (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7876780 | 0.77 | RXRA (0.41) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7881559 | 0.71 | RXRA (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7876892 | 0.71 | RXRA (0.49) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8347375 | 0.71 | RXRA (0.40) | RXRARXRBRXRGCYP26A1CYP3A4 | |
| SCHEMBL8349950 | 0.70 | RXRA (0.39) | RXRARXRBRXRGCYP26A1CYP3A4 | |
| SCHEMBL8350408 | 0.70 | RXRA (0.39) | RXRARXRBRXRGCYP26A1CYP3A4 | |
| SCHEMBL8353225 | 0.70 | RXRA (0.39) | RXRARXRBRXRGCYP26A1CYP3A4 | |
| SCHEMBL8352422 | 0.70 | RXRA (0.39) | RXRARXRBRXRGCYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935585-A | Biaromatic amido compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-08-10 | — | — | US | disclosed |