Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27368322 | 0.76 | SHBG (0.46) | TP53SHBG | |
| SCHEMBL20857002 | 0.74 | EPHX1 (0.45) | TP53SHBG | |
| SCHEMBL28415918 | 0.74 | SHBG (0.43) | SHBG | |
| SCHEMBL1754265 | 0.71 | EPHX1 (0.38) | TP53SHBGMEN1KMT2A | |
| SCHEMBL28854490 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL10885009 | 0.70 | SHBG (0.38) | TP53SHBGMEN1KMT2A | |
| SCHEMBL238323 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL3664930 | 0.66 | EPHX1 (0.38) | TP53SHBGMEN1KMT2A | |
| Water SCHEMBL28003932 | 0.66 | ALDH1A1 (0.31) | — | |
| SCHEMBL4303252 | 0.65 | SHBG (0.36) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643752-B1 | RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES | PROCTER & GAMBLE (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5877232-A | WEAR RESISTANCE; DIMENSIONAL STABILITY; SHRINKAGE INHIBITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0643752-A1 | RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0643752-A4 | RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES. | PROCTER & GAMBLE (US) | 1994-06-03 | — | — | EP | disclosed |
| WO-1993007230-A1 | RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES | THE PROCTER & GAMBLE COMPANY (US) | 1993-04-15 | — | — | WO | disclosed |