Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 5/20 | 0.64 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 6/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345943 | 1.00 | ATP6V1B1 (0.64) | ATP6V1B1ATP6AP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL8345939 | 1.00 | ATP6V1B1 (0.64) | ATP6V1B1ATP6AP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL8343521 | 0.90 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1SMN1; SMN2HRH4HRH3 | |
| SCHEMBL8345055 | 0.81 | ATP6AP1 (0.60) | ATP6V1B1ATP6AP1SMN1; SMN2PYGLFLT3 | |
| SCHEMBL8345059 | 0.81 | ATP6AP1 (0.60) | ATP6V1B1ATP6AP1SMN1; SMN2PYGLFLT3 | |
| SCHEMBL8345053 | 0.81 | ATP6AP1 (0.60) | ATP6V1B1ATP6AP1SMN1; SMN2PYGLFLT3 | |
| SCHEMBL8348529 | 0.79 | GABRP (0.52) | ATP6V1B1ATP6AP1SMN1; SMN2 | |
| SCHEMBL8343838 | 0.78 | IDO1 (0.51) | ATP6V1B1ATP6AP1SMN1; SMN2PYGL | |
| SCHEMBL8343834 | 0.78 | IDO1 (0.51) | ATP6V1B1ATP6AP1SMN1; SMN2PYGL | |
| SCHEMBL8350872 | 0.78 | ATP6V1B1 (0.67) | ATP6V1B1ATP6AP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981525-A | FOR THERAPY OR PROPHYLAXIS OF OSTEOPOROSIS,TUMOURS, ULCERS, AUTOIMMUNE DISEASES, LIPIDEMIC DISORDERS, HYPERCHOLESTEROLEMIC AND ATHEROSCLEROTIC DISEASES, AIDS ALZHEIMER'S DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |