Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714162 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6714168 | 0.84 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8347897 | 0.83 | KMT2A (0.44) | MEN1KMT2ASMN1; SMN2LPAR1ALDH1A1 | |
| SCHEMBL6713989 | 0.76 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8346261 | 0.76 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6718995 | 0.74 | MEN1 (0.45) | ANPEPMEN1KMT2ASMN1; SMN2CAPN1 | |
| SCHEMBL6717170 | 0.73 | STAT3 (0.55) | ANPEPMEN1KMT2ASMN1; SMN2CAPN1 | |
| SCHEMBL6717319 | 0.73 | ALDH1A1 (0.54) | ANPEPSMN1; SMN2CAPN1ALDH1A1 | |
| SCHEMBL6718999 | 0.72 | MEN1 (0.43) | ANPEPMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8345944 | 0.72 | MEN1 (0.43) | ANPEPMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |