Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345101 | 0.86 | ALDH1A1 (0.41) | SERPINE1ALDH1A1MAPTLMNATSHR | |
| SCHEMBL8091948 | 0.82 | SERPINE1 (0.41) | SERPINE1ALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL8123521 | 0.82 | SERPINE1 (0.53) | SERPINE1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL8171363 | 0.82 | SERPINE1 (0.40) | SERPINE1ALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL8342163 | 0.78 | SERPINE1 (0.37) | SERPINE1ALDH1A1MAPTLMNARAB9A | |
| SCHEMBL8043016 | 0.77 | MAPT (0.51) | SERPINE1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL8083684 | 0.77 | SERPINE1 (0.40) | SERPINE1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL9035671 | 0.76 | MAPT (0.48) | SERPINE1ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL8090682 | 0.76 | MAPT (0.42) | SERPINE1ALDH1A1MAPTLMNARAB9A | |
| SCHEMBL8344989 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |