Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | MAX | P61244 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083684 | 0.89 | SERPINE1 (0.40) | MAPTMEN1KMT2ACYP19A1SERPINE1 | |
| SCHEMBL8083652 | 0.87 | PPARG (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL8091742 | 0.85 | SERPINE1 (0.52) | MAPTMEN1KMT2ACYP19A1MYC | |
| SCHEMBL8098482 | 0.83 | MAPT (0.39) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8091948 | 0.82 | SERPINE1 (0.41) | MAPTMEN1KMT2ASERPINE1SMN1; SMN2 | |
| SCHEMBL8091935 | 0.82 | SERPINE1 (0.47) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8090679 | 0.82 | MAPT (0.43) | MAPTMEN1KMT2ACYP19A1MYC | |
| SCHEMBL8171363 | 0.82 | SERPINE1 (0.40) | MAPTMEN1KMT2ASERPINE1SMN1; SMN2 | |
| SCHEMBL8092259 | 0.79 | USP10 (0.44) | MAPTMEN1KMT2ASERPINE1NPC1 | |
| SCHEMBL8183715 | 0.78 | CFTR (0.40) | MAPTMEN1KMT2ACYP19A1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |