⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348517 | 0.73 | — | — | |
| SCHEMBL824109 | 0.73 | — | — | |
| SCHEMBL20353810 | 0.70 | NFKB1 (0.32) | — | |
| SCHEMBL29017 | 0.67 | MGLL (0.45) | — | |
| SCHEMBL19078891 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL13532538 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL17924963 | 0.60 | MGLL (0.38) | — | |
| SCHEMBL16376941 | 0.60 | — | — | |
| SCHEMBL13742892 | 0.59 | MGLL (0.41) | — | |
| SCHEMBL17369097 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143287-B2 | Thrombopoietin mimetics | STATEGICS, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100323965-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2010-12-23 | — | — | US | disclosed |