Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913903 | 0.87 | POLB (0.49) | KCNMA1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL7349273 | 0.79 | KCNMA1 (0.50) | KCNMA1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL8091948 | 0.79 | SERPINE1 (0.41) | KCNMA1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL8171363 | 0.78 | SERPINE1 (0.40) | HCAR3KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL8342528 | 0.76 | ALDH1A1 (0.38) | KCNMA1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL8123431 | 0.76 | MAPT (0.43) | KCNMA1HCAR3KMT2AMAPTMAPK1 | |
| SCHEMBL8621708 | 0.76 | MAPT (0.50) | KMT2AMAPTMAPK1L3MBTL1TDP1 | |
| SCHEMBL8083684 | 0.75 | SERPINE1 (0.40) | KMT2AMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL8090682 | 0.74 | MAPT (0.42) | KMT2AMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL8617767 | 0.74 | HSP90AA1 (0.42) | KMT2AMAPTMAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955461-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5750525-A | Quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |