Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278805 | 0.93 | NISCH (0.36) | SGMS2TRPM8CDK4CCND1HTR1A | |
| SCHEMBL6278806 | 0.93 | NISCH (0.36) | SGMS2TRPM8CDK4CCND1HTR1A | |
| SCHEMBL8347576 | 0.85 | L3MBTL1 (0.38) | ALDH1A1 | |
| SCHEMBL8542898 | 0.84 | DRD4 (0.34) | — | |
| SCHEMBL8505944 | 0.84 | DRD4 (0.34) | — | |
| SCHEMBL7684837 | 0.82 | NISCH (0.37) | SGMS2TRPM8CDK4CCND1ADRA2A | |
| SCHEMBL7684832 | 0.82 | NISCH (0.37) | SGMS2TRPM8CDK4CCND1ADRA2A | |
| SCHEMBL7093146 | 0.80 | — | — | |
| SCHEMBL8503437 | 0.80 | — | — | |
| SCHEMBL6979192 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790583-A | Method for detecting binding between MDM2 and proteasome | JANSSEN PHARMACEUTICA NV | 2010-07-28 | — | — | CN | disclosed |
| CN-1803798-B | Method for producing fungicide compand | BAYER AG | 2010-06-16 | — | — | CN | disclosed |
| CN-1803798-A | Method for producing fungicide compand | BAYER AG (DE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1057762-C | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AG (DE) | 2000-10-25 | — | — | CN | disclosed |
| CN-1222301-A | Process for preparing fungicidal compositions | BAYER AG (DE) | 1999-07-14 | — | — | CN | disclosed |
| US-5883250-A | ARYL SUBSTITUTED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0712396-B1 | SUBSTITUTED AZADIOXACYCLOALKENES AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1998-11-04 | — | — | EP | disclosed |
| US-5679676-A | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| CN-1132507-A | Substituted diazadioxacycloalkenes and their use as fungicides | BAYER AG (DE) | 1996-10-02 | — | — | CN | disclosed |