Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684837 | 1.00 | NISCH (0.37) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL6278806 | 0.89 | NISCH (0.36) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL6278805 | 0.89 | NISCH (0.36) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL8346622 | 0.82 | SGMS2 (0.40) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL8347576 | 0.80 | L3MBTL1 (0.38) | RAB9ANPC1MAPTTSHRMAPK1 | |
| SCHEMBL7669311 | 0.74 | SGMS2 (0.35) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL6965497 | 0.73 | NISCH (0.39) | NISCHSGMS2CDK4CCND1TRPM8 | |
| SCHEMBL6961704 | 0.72 | TDP1 (0.36) | SGMS2CDK4CCND1RAB9ANPC1 | |
| SCHEMBL6763809 | 0.72 | MGLL (0.33) | NPC1MAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6763805 | 0.72 | MGLL (0.33) | NPC1MAPTTSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462039-B1 | SUCH AS O-(2-((5,6-DIHYDRO-(1,4,2)DIOXAZIN-3-YL)-METHOXY-IMINOMETHYL)-BENZYL)1-(1 -METHYL-1H-INDAZOL-3-YL)ETHANONEOXIME; WELL TOLERATED BY PLANTS; CONTROLLING PLANT DISEASES BY TREATMENT OF AERIAL PARTS, SEEDS OR SOIL | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |