Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278806 | 0.90 | NISCH (0.36) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6278805 | 0.90 | NISCH (0.36) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8346622 | 0.85 | SGMS2 (0.40) | ALDH1A1 | |
| SCHEMBL7684832 | 0.80 | NISCH (0.37) | L3MBTL1MAPTLMNANPC1RAB9A | |
| SCHEMBL7684837 | 0.80 | NISCH (0.37) | L3MBTL1MAPTLMNANPC1RAB9A | |
| SCHEMBL6979192 | 0.78 | — | — | |
| SCHEMBL7093146 | 0.78 | — | — | |
| SCHEMBL8503437 | 0.78 | — | — | |
| SCHEMBL7950688 | 0.78 | NISCH (0.41) | L3MBTL1MAPTLMNANPC1HPGD | |
| SCHEMBL8505944 | 0.78 | DRD4 (0.34) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883250-A | ARYL SUBSTITUTED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |
| EP-0712396-B1 | SUBSTITUTED AZADIOXACYCLOALKENES AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1998-11-04 | — | — | EP | disclosed |
| US-5679676-A | Substituted azadioxacycloalkenes and their use as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |