SCHEMBL834683

SCHEMBL834683

c1ccc(Nc2cc[nH]n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.50
ALDH1A1 P00352 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
GAA P10253 4/20 0.50
HSD17B10 Q99714 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
RAB9A P51151 3/20 0.50
TSHR P16473 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ALPG P10696 1/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 2/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
PTGS2 P35354 1/20 0.44
HTR2B P41595 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28176926 0.81 KMT2A (0.58) ALDH1A1MEN1KMT2AGAACDK2
SCHEMBL1272593 0.81
SCHEMBL20448349 0.79 MEN1 (0.32) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL13844997 0.79 MAPK10 (0.46) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL9820118 0.79 TNIK (0.50) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL18118028 0.79 HAO1 (0.55) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL27606187 0.79 ADRA2A (0.46) MAPTALDH1A1KMT2ARAB9AKDM4E
SCHEMBL18901342 0.79 AURKA (0.69) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL16881732 0.77 EGFR (0.46) MAPTTSHRKDM4EMAPK1HTR2B
SCHEMBL27624897 0.77 GRM4 (0.48) MAPTALDH1A1MEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928455-A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES Bayer Healthcare, LLC (US) 2008-06-11 EP claimed
WO-2007027842-A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES BAYER HEALTHCARE LLC (US) 2007-03-08 WO claimed
EP-0618904-B1 NOVEL N-PHENYL AMINO PYRAZOLE DERIVATIVES AND MEANS AND PROCESS FOR COLOURING HAIR WELLA AG (DE) 1999-04-14 EP claimed
EP-0745067-A1 N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES BAYER AG (DE) 1996-12-04 EP claimed
WO-1995022530-A1 N-PYRAZOLYL ANILINES AND N-PYRAZOLYL AMINOPYRIDINES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-08-24 WO claimed
US-5430159-A N-phenylaminopyrazole derivatives as well as composition and process for the dyeing of hair WELLA AKTIENGESELLSCHAFT (DE) 1995-07-04 US claimed
US-4420308-A Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-13 US claimed
JP-8208620-A None JP disclosed
EP-4477271-B1 N-(PHENYL)-5-(HETEROARYL)-1H-PYRAZOL-3-AMINE DERIVATIVES AS TNIK INHIBITORS FOR USE IN THE TREATMENT OF CANCER KOREA RES INST CHEMICAL TECH (KR) 2026-05-13 EP disclosed
CN-120842212-A Anilino-pyrazole derivatives, compositions and methods thereof 昂胜医药有限公司 2025-10-28 CN disclosed
CN-120842212-A Anilino-pyrazole derivatives, compositions and methods thereof 昂胜医药有限公司 2025-10-28 CN disclosed
WO-2025136671-A1 ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
WO-2025136671-A1 ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF ENSEM THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
US-4952487-A 3-ANILINOPYRAZOLONE COUPLERS AND PHENOLIC OIL FORMER IN SILVER HALIDE EMULSION AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1990-08-28 US disclosed
US-4891057-A Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 US disclosed
EP-0269806-A1 Phenylpyrazole carbonic acid derivatives, their preparation and use as plant growth regulators and antidotes HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-08 EP disclosed
US-4420308-A Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-13 US disclosed
US-4419431-A One- or two-component diazo-type material with diphenyl diamine as light fade inhibitor VEB FILMFABRIK WOLFEN (DD) 1983-12-06 US disclosed
US-4317823-A FOR TREATMENT OF GASTROINTESTINAL DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1982-03-02 US disclosed
US-4045428-A Water-soluble reactive naphthylazonaphthyl dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed