Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834683 | 0.79 | MAPT (0.50) | KMT2ARAB9ANPC1KDM4EL3MBTL1 | |
| SCHEMBL29793056 | 0.76 | KIF11 (0.60) | ADRA2AADRA2BADRA2CRAD52KMT2A | |
| SCHEMBL1368828 | 0.76 | KIF11 (0.60) | ADRA2AADRA2BADRA2CRAD52KMT2A | |
| SCHEMBL1272593 | 0.73 | — | — | |
| SCHEMBL14941676 | 0.73 | ALDH1A1 (0.42) | KMT2AKDM4EALDH1A1KDR | |
| SCHEMBL25781511 | 0.72 | KARS1 (0.45) | ALDH1A1 | |
| SCHEMBL18725641 | 0.72 | TSHR (0.46) | ADRA2AADRA2BADRA2CRAD52KMT2A | |
| SCHEMBL29826892 | 0.72 | TSHR (0.46) | ADRA2AADRA2BADRA2CRAD52KMT2A | |
| SCHEMBL4037525 | 0.70 | TSHR (0.61) | RAD52KMT2ARAB9ANPC1KDM4E | |
| SCHEMBL16881732 | 0.70 | EGFR (0.46) | KDM4EMAPK1MAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85103468-A | Prepare the method for new compound and new purposes thereof | — | 1986-09-10 | — | — | CN | claimed |
| CN-1668601-A | N-substituted tricyclic 3-aminopyrazoles as PDFG receptor inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2005-09-14 | — | — | CN | disclosed |