Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346982 | 0.91 | CTSK (0.57) | CTSKGPR4 | |
| SCHEMBL3450766 | 0.88 | CTSK (0.77) | CTSKGPR4 | |
| SCHEMBL8344239 | 0.81 | CTSK (0.52) | CTSKGPR4 | |
| SCHEMBL13109183 | 0.77 | CTSK (0.68) | CTSKGPR4 | |
| SCHEMBL8344288 | 0.77 | GPR4 (0.52) | CTSKGPR4 | |
| SCHEMBL3915160 | 0.76 | CTSK (0.77) | CTSKGPR4 | |
| SCHEMBL13124829 | 0.76 | CTSK (0.60) | CTSKGPR4 | |
| SCHEMBL8344106 | 0.74 | CTSK (0.51) | CTSKGPR4 | |
| SCHEMBL8347898 | 0.73 | CTSK (0.59) | CTSKGPR4 | |
| SCHEMBL3451415 | 0.71 | CTSK (0.78) | CTSKGPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537111-B1 | HETEREOARYL NITRILE DERIVATIVES | NOVARTIS AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| WO-2004020441-A1 | HETEREOARYL NITRILE DERIVATIVES | NOVARTIS AG (CH) | 2004-03-11 | — | — | WO | disclosed |