Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879064 | 0.96 | LMNA (0.48) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8183397 | 0.91 | MAPT (0.50) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10587139 | 0.87 | MAPK1 (0.47) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8355907 | 0.87 | MAPK1 (0.47) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8186752 | 0.82 | LMNA (0.38) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27960535 | 0.81 | ALDH1A1 (0.39) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28565652 | 0.81 | ALDH1A1 (0.49) | RAB9AMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28566541 | 0.81 | ELANE (0.49) | RAB9AMAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL26097426 | 0.80 | APP (0.43) | RAB9AMAPTNPC1ALDH1A1TDP1 | |
| SCHEMBL28548550 | 0.78 | ALDH1A1 (0.56) | RAB9AMAPTNPC1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889181-A | REDUCING NITRO GROUP TO AMINE; DIAZOTIZATION; SULPHONATION;HYDROLYSIS | UNIVERSITY OF SHERBROOKE (CA) | 1999-03-30 | — | — | US | disclosed |