Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879064 | 0.86 | LMNA (0.48) | LMNASMN1; SMN2PSMB8MAPTRAB9A | |
| SCHEMBL8347105 | 0.82 | RAB9A (0.50) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL8186418 | 0.81 | MAPT (0.38) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL10719634 | 0.80 | PTPRC (0.42) | LMNASMN1; SMN2PSMB8MAPTRAB9A | |
| SCHEMBL8183397 | 0.79 | MAPT (0.50) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL28186501 | 0.78 | — | — | |
| SCHEMBL1861250 | 0.77 | HSPB1 (0.40) | LMNASMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL584790 | 0.76 | HSD17B1 (0.37) | — | |
| SCHEMBL27618213 | 0.76 | — | — | |
| SCHEMBL27787556 | 0.75 | TAAR1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0988037-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998033503-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-08-06 | — | — | WO | disclosed |